One of the benefits of enrolling in StemSave is the information on stem cell research we provide you. Adult dental stem cell research has accumulated from numerous clinical investigations in recent years. Two publications, Dental Economics and RDH Magazine (both published by PennWell Dental Group), provide a peer-reviewed article written by a leading stem cell researcher and a prominent dental professional.
When you enroll in StemSave, we provide reprints for you and your colleagues, or you may download the article here.
Upon completion of this course, the clinician will be able to
do the following:
- Understand the range of diseases for which stem cell therapies are
- Be knowledgeable about the various sources of stem cells and the advantages and disadvantages of each source;
- Understand the fundamental reasons for the effectiveness of stem cells and the meaning of tissue differentiation;
- Understand the basics of cryopreservation and the banking of stem cells.
Recent exciting discoveries place dentists at the forefront of engaging their patients in potentially life-saving therapies derived from a patient’s own stem cells located in deciduous and permanent teeth. Adult stem cells, including dental stem cells, have the potential, like bone marrow-derived stem cells and adipose-derived stem cells, to cure a number of diseases.
In medicine, stem cell-based treatments are being used and investigated for conditions as diverse as Parkinson’s disease, neural degeneration following brain injury, cardiovascular disease and autoimmune diseases. Stem cells will be used in dentistry for the regeneration of dentin and/or dental pulp, biologically viable scaffolds will be used for the replacement of orofacial bone and cartilage, and defective salivary glands will be partially or completely regenerated.
Dental stem cells can be obtained from the pulp of the primary and permanent teeth, from the periodontal ligament, and from associated healthy tissues. Exfoliating/extracted deciduous teeth and permanent teeth extracted for orthodontic treatment, trauma or dental implant indications are all readily available sources of dental stem cells. The harvest of these dental stem cells results in minimal trauma. Dental professionals have the opportunity to make their patients aware of these new sources of stem cells that can be stored for future use as new therapies are developed for a range of diseases and injuries.
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Stem Cells: Emerging Medical and Dental Therapies for the Dental Professional Dentaltown
Speaker: Jay B. Reznick, D.M.D., M.D.
The dental professional will play an important role in both the recovery and future use of stem cells in dental and medical regenerative and personalized therapies.
We now stand at the threshold of a potential revolution in medical treatment for diseases and disorders in which organs cease to function properly. Many other disorders, such as stroke, diabetes and Alzheimer's disease, cannot presently be treated by organ transplantation. Stem cell-based therapies are being investigated and many are at the clinical trial phase for the treatment of numerous conditions, including neurodegenerative conditions, liver disease, diabetes, cardiovascular disease, autoimmune diseases, musculoskeletal disorders, and for nerve regeneration following brain or spinal cord injury. As these clinical studies continue to advance in the years ahead, it is widely accepted that in order to avoid autoimmune rejection from donor tissues, while simultaneously maximizing on therapeutic efficacy, stem cells will be used to generate a individualized treatment for a specific patient.
The emerging field of “Personalized Medicine” is a popular topic in the media and generally refers to new medical technologies derived from a patient’s own stem cells. Within the context of Adult Dental Stem Cells, recent findings and scientific research supports the therapeutic use of the extremely potent mesenchymal stem cells found within the healthy pulp of deciduous and permanent teeth, as well as other accessible tissues harvested from the oral cavity. Their use can be applied to a multitude of regenerative and personalized medical therapies. Stem cells will be used in dentistry for the regeneration of dentin and/or dental pulp, biologically viable scaffolds will be used for the replacement of orofacial bone and cartilage, and defective salivary glands will be partially or completely regenerated.
While the promise of the immense scope and magnitude that stem cell therapies will have upon the population will only be fully realized in the future, Dental Professionals know that the critical time to act is now. The available opportunities to recover and cryopreserve their patients’ dental stem cells will have the greatest future impact if seized while their patients are young and healthy.
Upon completion of this course, participants should be able to achieve the following:
- Understand the basic science regarding the different types of stem cells
- Understand the various available sources of recovery for adult stem cells from within, and outside of, the oral cavity, as well as the advantages and disadvantages of each source
- Understand the benefits of recovering and cryopreserving dental stem cells
- Understand the clinical relevance in recovering dental stem cells
- Understand the potential uses of dental stem cells and their role in regenerative therapies
Dentaltown Magazine October 2008 Issue: Download the printed course and exam
Stem Cells: Emerging Medical and Dental Therapies and the Dental Professional Friends of Hu Friedy
Presenter: Gregory Chotkowski, D.M.D
Recent exciting new discoveries place dentists at the forefront of helping their patients benefit from potentially life-saving therapies derived from a patient’s own stem cells obtained from deciduous teeth and permanent teeth. We now stand at the threshold of a potential revolution in medical treatment for diseases and disorders in which organs stop working properly. At present, some such conditions, such as heart, kidney and liver disease, can be treated by transplantation of a replacement organ from another person. But demand for donor organs is far outstripping supply, and the failure rate of such surgery is quite high, mainly because of the problem of rejection. Many other disorders, such as stroke, diabetes and Alzheimer's disease, cannot presently be treated by transplantation. The great hope is that suitable stem cells, produced in large quantities through cell culture methods and injected into failing tissues and organs, will produce fresh, replacement cells to take over from lost or damaged ones. It is now known that adult stem cells taken from one area of the body can be transplanted into another area and grown into a completely different type of tissue. This ability to grow and regenerate tissues is the focus of the emerging field of personalized medicine which uses a patient’s own stem cells for biologically compatible therapies and individually tailored treatments. The Dental professional will play an important role in both the recovery and the use of these stem cells in both Dental and Medical regenerative therapies.
The Cell Revolution: How stem cells - particularly dental stem cells may be used in tissue regeneration and repair Dimensions of Dental Hygiene
Presenter: Ann Eshenaur Spolarich, RDH, PhD
Introduction:The recent discovery of stem cells in dental tissues has generated tremendous interest in both the lay and professional communities, as researchers explore the possibilities of using dental stem cells as a resource for tissue regeneration and repair. Numerous clinical trials are being conducted that seek to identify potential new medical treatments using stem cells. Stem cell-based therapies are being investigated for the treatment of many conditions, including neurodegenerative conditions; Parkinson's disease; musculoskeletal disorders; autoimmune, liver, and cardiovascular diseases; diabetes; and for nerve regeneration following brain or spinal cord injury.
Knowledge gained from this research contributes to the evolving field of "personalized medicine," which targets specific medical therapies to individual patients. Therapies that use a patient's own stem cells will allow for tissue regeneration and repair while minimizing risks for immune rejection that occur with donor tissues. Stem cell therapies will also include the use of genomic diagnostics and pharmaco - genomic drug therapies, all of which tailor medical treatment to the individual. Scientific research supports the use of dental stem cells for future use in a multitude of regenerative therapies.
Stem Cells: Emerging Medical and Dental Therapies and the Dental Professional
The New York State Dental Foundation
Presenter: Gregory Chotkowski, DMD
Introduction:The repair of damaged and diseased tissues and the creation of new organs is no longer the future, it is happening today. Daily, we hear the media reporting on stem cell breakthroughs and how they are being applied clinically to save lives. Stem cells and regenerative therapies are an emerging field and the basis for "personalized medicine".
Dental Professionals have the opportunity to participate at the genesis of this new and exciting area of biotechnology.
Dr. Gregory Chotkowski, DMD will present on the recently discovered and valuable source of stem cells found in the pulp of healthy teeth. His discussion will include basic stem cell science, the current research and the future they hold for both Dentistry and Medicine. StemSave, Inc., founded by Dr. Chotkowski, partners with Dental Professionals to provide individuals and families a cost effective, non-invasive methodology for the recovery and cryopreservation of powerful and valuable Adult Stem
Cells residing within the pulp of healthy teeth and other oral tissues.