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StemSave News and Events

03/07/2014 - StemSave Scientific Advisor, Gordana Vunjak-Novakovic, Develops Scaffold for Heart Tissue Regeneration
A team of researchers led by Dr. Gordana Vunjak-Novakovic [a member of StemSave’s Scientific Advisory Council has engineered a scaffold to facilitate the regeneration of heart muscle through the use of adult stem cells. In an animal model, Vunjak-Novakovic and her team created a scaffold using biodegradable chitosan and carbon nanofibers, infusing it with stem cells to provoke the regeneration of beating cardiomyocytes.

For the full story, click here.

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01/29/2014 - The Future of Regenerative Medicine is Now!
Don’t miss the “Stem Cell Universe” on the Science Channel’s program “Through the Wormhole” as host Morgan Freeman navigates the rapidly expanding world of Regenerative Medicine and Stem Cell Therapy. The program will feature several of the world’s leading scientists as they discuss the ability to grow organs and regenerate tissue. The program will offer insight into current and future applications of stem cells in treating disease, trauma and injury.

The “Stem Cell Universe” airs on February 3rd at 10pm Eastern Time. Tune in to learn how regenerative medicine will revolutionize the practice of medicine resulting in longer, healthier lives for individuals.

By banking their own valuable stem cells, families can ensure that they will have access to these emerging therapies in the near future. To learn more about banking stem cells, please visit www.stemsave.com or call 877-783-6728 (877-StemSave) today.

The Future of Regenerative Medicine is Now™
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01/20/2014 - StemSave Scientific Advisor, Gordana Vunjak-Novakovic, Leads Research Team to Differentiate Stem Cells into Lung Cells
A research team headed by Gordana Vunjak-Novakovic, of Columbia University, has successfully differentiated human stem cells into functional lung cells.

The technique, the first of its kind, represents a significant advance in the development of personalized treatments for patients suffering from a variety of lung issues. The team believes that the method, utilizing a patient’s own stem cells, could pave the way for generating lung grafts that avoid the risk of rejection during transplantation. The ability to regenerate lung cells also enables researchers to better study and understand lung diseases thereby accelerating the development of more effective treatments.

For the full story, click here.

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01/06/2014 - Conference on Cell Therapy for Cardiovascular Disease
Dr. Gordana Vunjak-Novakovic, PhD, a member of StemSave’s Scientific Advisory Council, will serve on the board of the Ninth International Conference on Cell Therapy for Cardiovascular Disease. The conference, being held by the Cardiovascular Research Foundation, is the preeminent gathering of the world’s top researchers in the field of stem cell therapy for cardiovascular disease.
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11/15/2013 - StemSave sets up collection center for 25th Annual Coat Drive
November 12th through December 31st, StemSave is partnering up with the New York Cares organization for its 25th Annual Coat Drive to collect coats and outerwear for those in need. StemSave is joining the NYC Police Department, Time Warner, Toshiba, NBC, Health Plus, Vornado and other concerned organizations and corporate citizens to serve our community and neighbors. If you are in the area please feel free to stop by StemSave’s corporate headquarters located at 526 W. 26th St, Suite #622 (Monday-Friday 9am-5pm) in NYC to donate any new or gently used coats. Thank you all in advance!
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11/11/2013 - StemSave Scientific Advisor Gordana V. Vunjak-Novakovic discovers method of regulating growth in kidney stem cells
The regulation of growth and metabolism of kidney stem cells with regional specificity using extracellular matrix derived from kidney

Abstract:

Native extracellular matrix (ECM) that is secreted and maintained by resident cells is of great interest for cell culture and cell delivery. We hypothesized that specialized bioengineered niches for stem cells can be established using ECM-derived scaffolding materials. Kidney was selected as a model system because of the high regional diversification of renal tissue matrix. By preparing the ECM from three specialized regions of the kidney (cortex, medulla, and papilla; whole kidney, heart, and bladder as controls) in three forms: (i) intact sheets of decellularized ECM, (ii) ECM hydrogels, and (iii) solubilized ECM, we investigated how the structure and composition of ECM affect the function of kidney stem cells (with mesenchymal stem cells, MSCs, as controls). All three forms of the ECM regulated KSC function, with differential structural and compositional effects. KSCs cultured on papilla ECM consistently displayed lower proliferation, higher metabolic activity, and differences in cell morphology, alignment, and structure formation as compared to KSCs on cortex and medulla ECM, effects not observed in corresponding MSC cultures. These data suggest that tissue- and region-specific ECM can provide an effective substrate for in vitro studies of therapeutic stem cells. Click Here to Read the Full Text
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06/25/2013 - StemSave Science Advisor, Dr. Gordana Vunjak-Novakovic Engineers Bone Tissue with Human Stem Cells

Engineering bone tissue substitutes from human induced pluripotent stem cells

Abstract:

Congenital defects, trauma, and disease can compromise the integrity and functionality of the skeletal system to the extent requiring implantation of bone grafts. Engineering of viable bone substitutes that can be personalized to meet specific clinical needs represents a promising therapeutic alternative. The aim of our study was to evaluate the utility of human-induced pluripotent stem cells (hiPSCs) for bone tissue engineering. We first induced three hiPSC lines with different tissue and reprogramming backgrounds into the mesenchymal lineages and used a combination of differentiation assays, surface antigen profiling, and global gene expression analysis to identify the lines exhibiting strong osteogenic differentiation potential. We then engineered functional bone substitutes by culturing hiPSC-derived mesenchymal progenitors on osteoconductive scaffolds in perfusion bioreactors and confirmed their phenotype stability in a subcutaneous implantation model for 12 wk. Molecular analysis confirmed that the maturation of bone substitutes in perfusion bioreactors results in global repression of cell proliferation and an increased expression of lineage-specific genes. These results pave the way for growing patient-specific bone substitutes for reconstructive treatments of the skeletal system and for constructing qualified experimental models of development and disease.
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07/09/2012 - StemSave Scientific Advisor, Gordana Vunjak-Novakovic, Spearheads Research Team Growing Replacement Bone From Stem Cells
A team led by Gordana Vunjak-Novakovic, of Columbia University has successfully grown a variety of bone structures utilizing a scaffold infused with stem cells.

The team has grown more than 50 healthy bones from stem cells. The team is experimenting with a variety of scaffolding materials, including bone stripped of all cellular material as well as silk scaffolds developed by Tufts University. The scaffolding with the stem cells are housed in a bioreactor which nourishes and directs the stem cells to regenerate and differentiate into newbone. As the new bone develops, the scaffolding material dissolves, resulting in new, fully-functioning bone.

For the full story, click here.

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05/18/2012 - StemSave Science Advisor, Dr. George T.-J. Huang, Takes on Leading Role in Advancing Stem Cell Research
StemSave Science Advisor, Dr. George T.-J.Huang, DDS, MSD, DSc has accepted the position of Director of Stem Cells and Regenerative Therapies in the Department of Bioscience Research in the College of Dentistry at the University of Tennessee.

Dr. Huang previously served as the Chair and Herbert Schilder Professor in Endodontics and Director, Postgraduate Program in Endodontics of Boston University’s Henry M. Goldman School of Dental Medicine. Dr. Huang’s current research interest is in the area of stem cells and regenerative medicine with particular emphasis on the generation and characterization of induced pluripotent stem cells (iPSCs) from dental stem cells, creating an indefinite stem cell source for tissue regeneration and an invaluable tool for the study of disease.

We congratulate Dr. Huang on his well-earned advancement and anticipate the many future contributions he will make as an acknowledged leader of his field.

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04/08/2012 - StemSave Scientific Advisor Dr. Gordana Vunjak-Novakovic to Serve as Keynote Speaker at The European Life Sciences Summit 2012
StemSave Scientific Advisor Dr. Gordana Vunjak-Novakovic will serve as a keynote speaker at Biomedica’s European Life Sciences Summit on April 19th. The European Life Sciences Summit provides a platform for the foremost researchers and innovators from around the world to convene for discussions and presentatioons on the latest advances in all aspects of Life Sciences.

Prof. Dr. Gordana Vunjak-Novakovic is a Mikati Foundation Professor of Biomedical Engineering, Vice-Chair & Professor of Biomedical Engineering and Medical Sciences, and Director of Laboratory for Stem Cells and Tissue Engineering at Columbia University. She will be presenting on Cell-instructive biomaterials for tissue engineering and regenerative medicine.

As one of the most rapidly advancing fields in modern medicine, regenerative medicine and the study of stem cells will be a prominent focus at the Summit. For more information of about The European Life Sciences Summit, click here.

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03/28/2012 - StemSave’s Chief Scientific Advisor, Dr. Jeremy Mao Presented at this year’s AADR Annual Meeting
Dr. Jeremy Mao, StemSave’s Chief Science Advisor presented at the American Association for Dental Research (AADR) Annual Meeting in Tampa, FL this past week.

Dr. Mao, DDS, PhD, a leading stem cell researcher and co-head of Columbia University’s Center for Craniofacial Regeneration discussed several recent advances in stem cell dental treatments and the likely impact stem cells will have on the practice of dentistry.

To view a full list of Dr. Jeremy Mao's research presentations at the AADR annual meeting, as well as other similar research, click here.

Beyond the world of dentistry, the regenerative properties of stem cells are being used to treat many forms of trauma, genetic conditions, degeneration, disease and natural aging. As these therapies continue to develop, access to your own mesenchymal stem cells becomes increasingly important.

A valuable population of mesenchymal stem cells can be readily obtained from the dental pulp in teeth. Dental pulp stem cell acquisition can be accomplished by preserving a shed baby tooth in a timely manner or coordinating with your dentist to obtain the stem cells from a wisdom tooth upon extraction. Once the stem cells from dental pulp of teeth have been properly preserved, they would be available to the patient to use in a potentially broad range of regenerative treatments to address a wide variety of disease, trauma and injury such as Parkinson’s disease, amyotrophic lateral sclerosis, spinal cord injury, burns, heart disease, diabetes, and arthritis.

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03/28/2012 - StemSave Scientific Advisor Gordana Vunjak-Novakovic to Present at the EGSC at Columbia University
Professor Gordana Vunjak-Novakovic, a leading researcher in the field of biomedical engineering, will be speaking on Biomedical Entrepreneurship this coming Wednesday, March 21 at Columbia University.

Gordana Vunjak-Novakovic is the Mikati Foundation Professor of Biomedical Engineering and Medical Sciences and is the Director of the Laboratory for Stem Cells and Tissue Engineering at Columbia University. She was recently inducted into the National Academy of Engineering, and is also a fellow of the American Institute for Medical and Biological Engineering. Professor Vunjak-Novakovic received her B.S., M.S., and Ph.D. in chemical engineering from the University of Belgrade.

Presenting with Professor Gordana Vunjak-Novakovic is Dr. Yiannis Monovoukas; chairman, president, and chief executive officer of TEI Biosciences Inc., a privately held regenerative medicine company that develops novel biologic products for a broad spectrum of soft tissue repair, reinforcement, and reconstruction applications. Dr. Monovoukas holds an MS and PhD in chemical engineering from Stanford University and an MBA from Harvard Business School.

To learn more about this Wednesday’s lecture and stem cell research at Columbia University, click here.

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03/06/2012 - StemSave Celebrates National Dentist Day
On National Dentists Day (March 6th, 2012), we at StemSave celebrate and acknowledge all dentists and the important role they play as trusted health advisors in the health and happiness of their patients. With the link between oral health and systemic health well established, dentists are playing an increasing role in the overall health of their patients. And with the valuable and powerful stem cells found in teeth, dentists are at the forefront of regenerative medicine and playing an important role in the future health of their patients. Please join us on March 6th to praise Dentists on National Dentists Day on Facebook (StemSave, Inc) and Twitter (@StemSave).
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02/24/2012 - StemSave Attends Nelson Mandela Foundation Fundraiser Hosted by President Bill Clinton
StemSave joined other supporters of the Nelson Mandela Foundation for a fundraiser hosted by President Bill Clinton at his New York City Offices. The gathering, which was also attended by former ambassador to South Africa, Delano Lewis, raised funds for the Nelson Mandela Foundation’s ‘Mandela Centre of Memory.’ The Centre serves as a vital platform to learn from and apply President Mandela’s philosophy of reconciliation and dialogue when dealing with conflict and difficult social issues. To learn more about the foundation and its mission and programs to address injustices, conflict and difficult social issues, please visit www.nelsonmandela.org
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02/10/2012 - StemSave To Attend The 2012 NY Stem Cell Summit
StemSave CEO, Art Greco is to be present at this year’s annual New York Stem Cell Summit. Established 7 years ago, the summit is one of the most prestigious and progressive stem cell related conferences. The NY Stem Cell Summit features some of the top stem cell companies in the world presenting the latest information on stem cell based therapies for cardiovascular repair, nerve regeneration, orthopedics, diabetic treatment cancer and autoimmune disease. Company profiles are available on the Stem Cell Summit website.
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02/08/2012 - StemSave Celebrates National Children’s Dental Health Month February 2012

The American Dental Association sponsors National Children’s Dental Health Month every February to raise awareness about the importance of oral health. The 2012 NCDHM campaign brings together thousands of dedicated dental professionals, health care providers and others to promote the benefits of good oral health to children and adults, caregivers, teachers, and many others.

Good oral health is obviously important for your overall health, but did you know that there are stem cells in your child’s baby and wisdom teeth that are just as valuable to their future health? With the knowledge from recent medical research, StemSave gives you the opportunity to save these cells for future use in developing medical treatments for your family.

To view the NCDHM Program Planning Guide and download fun activity sheets for kids, click here.

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01/14/2012 - StemSave attends Nelson Mandela Foundation luncheon in New York City
StemSave CEO, Art Greco, attended a special luncheon in New York City, hosted by Chartis, to launch a fundraising initiative for the Nelson Mandela Foundation and to support the Mandela Centre of Memory. The Centre serves as a vital platform to learn from and apply President Mandela’s philosophy of reconciliation and dialogue when dealing with conflict and difficult social issues. To learn more about the foundation and its mission and programs to address injustices, conflict and difficult social issues, please visit www.nelsonmandela.org
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01/14/2012 - StemSave Concludes Successful 2011 Partnership With NY Cares Coat Drive
The StemSave coat drive, in which we partnered up with NYCares, was a success! Thank you to everyone who donated coats! We wish you all a safe and warm winter season. If you are still interested in donating coats, the drive continues at the NY Cares collection center located at 208 W 29th St # 409 New York, NY 10001-5590 through January 19th.
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12/21/2011 - StemSave’s Chief Science Advisor Dr. Jeremy Mao Meets with Future Leaders of Dental Stem Cell Research
On December 14th, Holly Flores and Austin Wild, two high school finalists in the Siemens Science Competition from Long Island, New York were invited to Columbia University’s Center for Craniofacial Regeneration for a guided tour and question and answer session with StemSave’s Chief Science Advisor, Dr. Jeremy Mao. The two students presented their own research from the Siemen’s Competition on the Extracellular Matrix in Dental Pulp Stem Cell Differentiation to Dr. Mao and StemSave’s CEO Art Greco. StemSave congratulates the two students for making it to the regional finals in the Siemens Competition and commends them for their outstanding work in Dental Stem Cell Research.
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12/06/2011 - StemSave sets up collection center for 23rd Annual Coat Drive
November 15th through December 31st, StemSave is partnering up with the New York Cares organization for its 23rd Annual Coat Drive to collect coats and outerwear for those in need. StemSave is joining the NYC Police Department, Time Warner, Toshiba, NBC, Health Plus, Vornado and other concerned organizations and corporate citizens to serve our community and neighbors. If you are in the area please feel free to stop by StemSave’s corporate headquarters located at 526 W. 26th St, Suite #622 (Monday-Friday 9am-5pm) in NYC to donate any new or gently used coats. Thank you all in advance!
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11/07/2011 - Dr. Jeremy Mao, DDS, PhD Honored with Achievement Award
StemSave’s Chief Science Advisor, Doctor Jeremy Mao, DDS, PhD was the recipient of this year’s prestigious Henry Spenadel Award.   StemSave was privileged to sponsor the NYCDS [New York County Dental Society] award dinner where Dr. Mao’s presentation addressed advances in regenerative medicine and the differentiation properties of stem cells in teeth.  Congratulations to Dr. Jeremy Mao.
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10/26/2011 - StemSave and Global Innovation Partner on Education Initiative
StemSave recently partnered with Global Innovation, a cross-disciplinary international educational initiative supported by the Danish government to administer a research project based on the current trends and future outlook of regenerative medicine among university aged students.
With the Danish government’s emphasis on innovation as a prime driver of Danish competitiveness and success in global markets [in 2010 Denmark was ranked 5th in the Global Innovation Index] the Global Innovation initiative seeks to facilitate innovation and learning internationally with an emphasis on new and emerging technologies and trends.  
Given the transformative impact stem cell based regenerative medicine will have on the practice of medicine and StemSave’s leading role in the emerging field of regenerative medicine, StemSave was delighted to participate in the program.  The StemSave program brought together students from two Danish Universities, TEC and CpHWest, to study the current state of the industry, emerging trends, the impact regenerative medicine is likely to have on the health and longevity of individuals, and the modes and methods of information dissemination.  
On October 13th, the students came to StemSave’s corporate base in New York City and presented the CEO, Art Greco, with new data and ideas pertaining to the growth in youth knowledge of regenerative medicine and the value of stem cell banking. StemSave kindly thanks Global Innovation for the opportunity to work with the students of TEC and CphWest and looks forward to future innovation projects with Global Innovation and the Danish government.

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09/30/2011 - StemSave AAOMS Conference Highlights
Earlier this month, StemSave participated in the 93rd Annual Meeting of the Association of Oral and Maxillofacial Surgeons in Philadelphia, PA. During the conference some very important news was announced: following a rigorous review and due diligence process, StemSave was chosen as an Approved Partner by ASI of the American Association of Oral and Maxillofacial Surgeons – AAOMS. StemSave is the only stem cell banking service to receive this coveted designation and we are delighted to be a part of the AAOMS ASI partner program. We believe our selection is a result of a combination of influences, such as, our industry leading network [thanks to you], our support of stem cell research, our exemplary Science Advisory Council, our proprietary web based platform designed to easily integrate into busy dental practices, our patented transport kit, our adherence to FDA minimal manipulation guidelines and our continuous commitment to excellence. StemSave was featured an exhibition at the AAOMS/ASI Partners Pavilion. In addition, Dr. Jeremy Mao, Chief Science Advisor to StemSave and Director of the Tissue Engineering and Regenerative Medicine Laboratory (TERML) at Columbia University presented Highlights of Translational and Clinical Research in Stem Cell Therapy to the conference attendees.
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06/09/2011 - Dental Stem Cells could be Lifesavers in the Long Run

Reprinted from The Los Angeles Daily News by Stephanie Cary

People often dread going to the dentist, many of them putting it off for as long as possible, but getting to the dentist early in life could benefit you in the long run, and for reasons that have little to do with your teeth.

Research is underway to determine the possibility of using dental stem cells as treatment for various cancers and injuries, much like the use of stem cells from umbilical cord blood, amniotic fluid and bone marrow.

There are currently no Food and Drug Administration-approved treatments using dental stem cells, but that hasn't stopped some dentists from offering their patients the opportunity to harvest them through companies such as StemSave and Store-A-Tooth.

"When I heard how easy it is to harvest the stem cells from teeth and the potential uses for them, it seemed like something that was a great service we could provide for our patients for a number of reasons," said Dr. Jay Reznick, who uses StemSave at his Tarzana practice, Southern California Center for Oral and Facial Surgery.

Those reasons include the accessibility of the dental tissue in which the stem cells are found.

The harvesting process is done when patients come in to have a healthy tooth - a tooth with blood supply - removed, whether it be a wisdom tooth, a baby tooth or a tooth being taken out for orthodontic purposes, Reznick says.

He says it's best to harvest dental stem cells in a child under 18 because as the cells age the stem cells become less viable.
The process does not increase soreness or require extra healing time for the patient, Reznick says.

Once the tooth is removed, instead of throwing it away, the doctor or dentist puts the tooth in a vial and ships it to StemSave overnight. If stem cells can be harvested from the tooth, they are preserved through a process called cryopreservation.

The mesenchymal stem cells found in dental tissue are thought to be best used to rebuild bone, cartilage, nerve tissue or muscle tissue, Reznick says. Researchers also have used these stem cells to become insulin-producing cells inside the pancreas so some day they may be able to treat diabetes, Reznick says.

"Even though there's not a clinical use that's FDA approved at the moment, there's a lot of research that's being done. In fact, in the lab they are growing jawbones in mice from dental stem cells," Reznick said.

"They are also generating muscle tissue and nerve tissue, so there's a lot of research going on at a very rapid pace," he said. "More and more researchers are getting involved in this across the world, to be able to use these very accessible stem cells in order to be able to treat diseases and conditions in patients."

Dr. David Dann offers StemSave though his Tarzana practice, even though he says dental stem cell research is in its infancy.

He says he believes in the current research so much he had his son's dental stem cells harvested with StemSave.

"I remember when my kids were born, people were starting to save the stem cells from umbilical cords and it was a little bit unknown to us at that time, so I feel like I missed that opportunity in not doing that," Dann said.

"And I feel that saving the stem cells from the teeth is simple. I think it's a simple procedure. It's easily accomplished."

The extended opportunity to harvest dental stem cells is another reason Reznick decided to get on board.

Like Dann, when his children were born Reznick was told about storing stem cells from the umbilical cord. At the time, there were no clinical treatments that the stem cells could be used for and the process was expensive. So, Reznick passed on the one-time opportunity.

Since then, numerous clinical uses have been developed for stem cells from umbilical cord blood including treating lymphoma, leukemia and other cancers, Reznick says.

"Umbilical cord blood and amniotic fluid are also great sources of stem cells. However, you really only have one opportunity to harvest those cells - basically when the child is born," Reznick said.

"If you miss that opportunity then it's gone, whereas with dental stem cells you have multiple opportunities throughout the child's life to be able to harvest and preserve the stem cells later on."

The cost of storing dental stem cells is also cheaper.

There is a $600 initial fee and a $100 annual fee to join the StemSave bank. In contrast, to bank umbilical cord blood with StemCyte, the initial fee is more than $2,000 and there is a $125 annual fee.

Despite the possible uses of dental stem cells, neither Reznick nor Dann have many patients taking advantage of the opportunity. But they both expect that to change as more information is made available.

"It's just a matter of time - these clinical treatments involving stem cells from the teeth are proven and approved," Reznick said.

"In the future, I expect to see not only an increase in the number of uses that are found from these cells, but I think you will also see some clinical applications that are going to become clinically approved and fairly common."

For more information about harvesting dental stem cells, go to www.stemsave.com.

The complete article can be found here:

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05/12/2011 - CBS News - Life Saving Teeth? Why to Save your Children's baby teeth

 WPEC - CBS12.com

WEST PALM BEACH -- Could your teeth hold the key to a life-threatening illness years down the road? Local families are getting a new outlook on what to do with their children's baby teeth or painful wisdom teeth.

For years, pregnant women have been given the option of storing cord blood for stem cells in case of future disease or injury. Now, there's a much more readily-accessible source of stem cells, and it's in your child's mouth.

Rebecca Fogel recently underwent surgery to remove two impacted teeth. But instead of discarding them, local oral surgeon Dr. Andrew Slavin suggested they be saved for what's inside, stem cells.

"Impacted wisdom teeth are a great source of these stem cells," said Dr. Slavin.

It was recently discovered that the dental pulp inside wisdom teeth and baby teeth contains a rich source of stem cells. Stem cells are different than other cells in the body because they regenerate and produce specialized cell types. They heal and restore skin, bones, muscles and nerves. That has opened the door to new medical treatments being developed to treat a range of diseases and injuries thought to be difficult or impossible to treat.

So how does it work? The surgeon extracts the tooth, puts it in a special solution to preserve it and sends it to a company called StemSave. StemSave retrieves the stem cells and stores them until you need them.

"If a teenager had his wisdom teeth out and later in life in their third decade or fourth decade of life, they developed a chronic disease, a muscle condition a problem with their liver or their heart, they could actually use their stem cells their own stem cells and not have the fear of rejection from using someone else's tissue," said Dr. Slavin.

StemSave's initial fee is $590, then $100 a year for storage.

"It was a no brainer for me. It was an insurance policy for her in the future. So we're really glad we went ahead and did it," said Rebecca's mother Cathleen Fogel.

Cathleen isn't worried about Rebecca getting sick in the future. She's hoping for a future treatment for Rebecca's cerebral palsy, and Rebecca is banking on those teeth to provide a cure.

"Hopefully one day we can repair some of the damage that Rebecca suffers from her cerebral palsy and that she'll be able to walk and do things easier," said Cathleen.

"Can we get rid of it?" asked Rebecca.

"Hopefully, God willing, we'll see. We don't know what the future holds as technology advances," said Cathleen.

 

 

http://www.cbs12.com/articles/teeth-4732394-cells-liz.html#ixzz1M9vwIvq9

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01/18/2011 - Miami Herald - Pulled Teeth Stored for Stem Cells


Dentists are pulling teeth, then having the stem cells stored in case they're needed to fight disease.

By Fred Tasker, photos by Marice Cohn Band.

Naidelys Montoya didn't wait for her son's baby teeth to fall out. She took the boy to an oral surgeon to have two of the loose ones extracted.

``He was a bit scared,'' said Montoya, of Hialeah. ``He's not that brave.''

The dentist shipped the teeth in a temperature-controlled steel container to a lab in Massachusetts, where their stem cells will be spun out, frozen to more than 100 degrees below zero and stored -- in case her son, Raul Estrada, 6, might need them for a future illness.

``I believe in this,'' Montoya said. ``I did as a precaution against things that could happen in the future.''

Montoya and her son have joined a major new medical movement.

In South Florida and around the world, dentists are extracting baby teeth, wisdom teeth and even healthy adult teeth, and researchers are spinning out stem cells that they believe can be used to regrow lost teeth, someday even to repair damaged bones, hearts, pancreases, muscles and brains.

It could put the Tooth Fairy out of business.

``These are teeth we've been discarding as dental waste,'' said Dr. Jeffrey Blum, the Miami Beach oral surgeon who pulled Raul's teeth. ``We might as well get some use out of them.''

``I can't help but feel excitement for their potential use in regenerating different tissues in the human body,'' said Dr. Jeremy Mao, director of the Regenerative Medicine Laboratory at Columbia University. Mao also is chief science advisor to StemSave, a New York City company that freezes the stem cells and stores them for later use.

There are concerns. It's expensive, costing $590 upfront plus $100 a year to store the stem cells from up to four teeth for up to 20 years. It's speculative, with the first FDA-approved practical use of such stem cells years away.

``Every treatment using dental stem cells is still in the clinical testing phase, and won't be ready for general use for at least five years,'' said Art Greco, StemSave's CEO.

Montoya understands: ``Things are evolving so quickly, who knows what they will be able to do in 15 or 20 years?'' Other researchers welcome the new source of stem cells.

``Perhaps it does make sense to save'' dental stem cells, said Dr. Joshua Hare, director of the Interdisciplinary Stem Cell Institute at the University of Miami Medical School, who is not involved with dental stem cells. ``Within human adults and children there are lots of reservoirs of stem cells. We get them from bone marrow; others use umbilical cord blood. It seems teeth are also a good source.''

The National Institutes of Health concluded in 2003 that teeth are a rich source of stem cells. Every child has about 20 baby teeth that fall out between ages 6 and 12. Adolescents have wisdom teeth that often are removed between ages 14 and 25 because they crowd the jaw or grow in crookedly.

Blum and other oral surgeons must extract baby teeth before they fall out naturally, so they still have a blood supply to keep them healthy. He puts them in a temperature-controlled steel container and overnights them to the StemSave facility.

Stem cells are the body's repair system, Hare said. Stem cells beneath the skin are constantly spinning off new skin cells to replace skin that is sloughed off or damaged in daily life. The same is true for hearts, livers, pancreases -- except that as the body weakens from age, injury or disease, those stem cells start to lose the ability to keep up and need help. Today, stem cells from bone marrow, blood and now perhaps teeth can be reprogrammed to help those ailing organs.

Also, by using these stem cells researchers avoid involving human embryonic stem cells, which are controversial because their creation involves destroying human embryos.

The first practical use of dental stem cells probably will be to repair human teeth and jawbones, researchers say. At Boston University's School of Dental Medicine, researchers have used stem cells from baby and wisdom teeth to generate dental pulp, the soft interior of a tooth, and dentin, its hard white casing.

Now they are inserting the material into a broken human tooth and implanting it into a mouse to access a blood supply. When the technology reaches humans, the pulp material would be injected into a spongy ``scaffold'' where a tooth has been removed and prompted to grow into a human tooth. It's at least five years away.

Across the world, the use of stem cells to heal the human body is exploding. At UM Med School, Hare is doing human trials using stem cells from bone marrow to inject around hearts damaged by heart attacks, hoping to regenerate damaged heart tissue.

For years, stem cells from umbilical cord blood have saved the lives of patients with leukemia, lymphoma, multiple myeloma, aplastic anemia, sickle cell and other diseases.

Umbilical cord blood is being donated both to private labs for use only by the donor's family, and also to public donation centers that are opening across South Florida.

In Broward County, Memorial Health Care System, Memorial Hospital West in Pembroke Pines, Memorial Regional in Hollywood and Memorial Hospital in Miramar have opened or are opening public cord-blood donation centers.

Women giving birth may donate their umbilical cords without charge. The blood is flown to a lab at Duke University in North Carolina, where the stem cells are spun off and stored at subfreezing temperatures. The cells become part of a National Cord Blood bank where they are available to any patient in the world if an adequate cell match can be determined.

South Miami Hospital opened a similar center in 2009.

Cord blood stem cells collected for private use have been more speculative because of the rarity of diseases it can treat. A 2009 study published in the peer-reviewed journal Obstetrics and Gynecology said cord blood stem cells in private banks have been used in less than half of one percent of cases over the past 10 years. But stem cells in public cord blood cell banks are in short supply, especially for Hispanics and African Americans.

So far, only private banks are storing dental stem cells, although Mao says a public bank would be valuable and appropriate.

The American Dental Association, while cautiously optimistic about the potential of dental stem cells, urges parents considering banking their children's dental stem cells to consider both the cost and the rarity of use before joining private donation programs.

``That's the question people have to ask themselves,'' Blum said. ``Am I saving this for no reason? Is it worth what I'm paying? Essentially it's an insurance policy.''

Another important question, of course, is what Blum tells kids when he ships away their baby teeth before they can collect from the Tooth Fairy.

He shrugs: ``I leave that up to the parents.''

Read more: http://www.miamiherald.com/2011/01/17/v-fullstory/2020617/pulled-teeth-stored-for-stem-cells.html#ixzz1BOzgPnQi


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12/14/2010 - DENTAL STEM CELLS EXPANDING MEDICAL LANDSCAPE AND STEM CELL RESEARCH
First-Ever International Conference on Dental and Craniofacial Stem Cells

The First International Conference on Dental and Craniofacial Stem Cells (ICDCSC) will take place on April 27 – 29, 2011 at the New York Academy of Sciences in New York City.  This will be the first ever assembly of the world’s most prominent scientists in the field of dental and craniofacial stem cells, as well as the emerging field of regenerative dental medicine.

More than 300 participants from scientific research, industry, government agencies such as NIH and FDA will come together to encourage cross-disciplinary alliance and catalyze the advancement of dental and craniofacial stem cell research.  Dr. Jeremy Mao of Columbia University, Dr. Darwin Prockop of Texas A&M Medical Center, and Dr. Pamela Robey and Dr. Nadya Lumelsky of the NIH.

We are delighted that StemSave Chief Science Advisor Dr. Jeremy Mao is amongst the distinguished researchers chosen to lead the symposium.  Current studies show the potential of dental stem cells to significantly impact treatments that run the gamut from dental implants to reconstructive surgery, as researchers have been able to regrow both teeth and jawbone.  Moreover, dental stem cells demonstrate tremendous promise in advancing the field of regenerative medicine, which continues to make important strides in addressing degenerative conditions, disease, congenital anomalies, trauma and organ repair and replacement . 

For more information on the symposium, email: mmw7@columbia.edu


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06/02/2010 - StemSave, Inc. teams up with pediatric dentists at Jamaica Hospital to offer New York families access to valuable stem cells.
StemSave, Inc teams up with pediatric dentists at Jamaica Hospital to offer New York families access to valuable stem cells.

NEW YORK, NY, June 1, 2010 – StemSave™ Inc., the market leader in the field of stem cell recovery and cryo-preservation, announces they are now working with pediatric dentists at Jamaica Hospital to use a new and innovative medical approach to stem cell banking to make it easier for local families to bank their children's stem cells. The partnership marks the first time dentists at Jamaica Hospital will help store their patients’ own stem cells collected from baby teeth, as well as permanent and wisdom teeth, for potential use in medical treatments.
Stem cells are the basis of the emerging field of regenerative medicine.  According to research released by the National Institutes of Health (NIH), “Regenerative Medicine is the process of creating living, functional tissues to repair or replace organ function lost due to age, disease, damage or congenital defects.  This field holds the promise of regenerating damaged tissues and organs in the body by stimulating previously irreparable organs to heal themselves.  Regenerative medicine also empowers scientists to grow tissues and organs in the laboratory and safely implant them when the body cannot heal itself.” 
"What makes this breakthrough significant is it gives parents an affordable and convenient opportunity to save their children's stem cells," said Dr. Silvestro Iommazzo, Associate Director Pediatric Dentistry at Jamaica Hospital. “With advancements in stem cell technologies and the discovery of dental stem cells, parents have the opportunity during their children’s natural tooth development - baby teeth and wisdom teeth are ideal stem cell candidates - to recover and bank their own stem cells for potential use in future regenerative medical treatments.”
“We’re proud to extend our network to Jamaica Hospital, and give patients the chance to participate in the most exciting and cutting edge stem cell breakthroughs today,” said Art Greco, CEO of StemSave. “We’re seeing remarkable applications in labs across the country, and we believe now is the time to save your own stem cells so families have the opportunity to take part in the treatments of the future.”
Dr. Iommazzo,  along with other pediatric dentists at Jamaica Hospital, work closely with StemSave and parents to ensure that the process is safe, easy, and efficient. Dr. Iommazzo points out that collecting stem cells from teeth is non-invasive because it is done as part of routine dental procedures and at a point when the tooth is already going to come out. 
Interested parents should meet with a dentist to find out if their child is a candidate for stem-cell preservation. An eligible tooth has an intact blood supply and should be healthy and free from infection. The ideal baby tooth is a newly loose canine or incisor. An excessively loose tooth or one that has already fallen out is not a viable option because the blood supply to the dental pulp is cut off.  While it is better to collect stem cells from younger patients, adults, up to approximately 55 years old, are also eligible to have stem cells collected from their teeth.
StemSave’s network of dentists is the largest in the US and continues to expand rapidly. Through StemSave, dentists are now able to play a greater role in the overall health of their patients by participating in groundbreaking stem cell recovery. 
The science and application of stem cells to treat today’s most difficult diseases and injuries is no longer science fiction.  With the recent news that stem cells have been used in organ transplants and tooth regeneration, coupled with the US Army’s $250 million investment in regenerative therapies, the promise of stem cells is being recognized today.
If you are interested in banking your child's stem cells from their teeth, please visit www.StemSave.com or call Jamaica Hospital's Dental Clinic at 718-206-6980.

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05/25/2010 - Journal of Dental Research: Body's Own Stem Cells Lead to Tooth Regeneration
From Dentistry IQ: Stem cells of body lead to tooth regeneration NEW YORK--People who have lost some or all of their adult teeth typically look to dentures, or more recently, dental implants to bridge the gap between a toothless appearance. But this appearance can have a host of unsettling psycho-social ramifications and a tooth-filled grin that is not without pain and discomfort. Despite being the preferred treatment for missing teeth today, dental implants can fail and have no ability to “remodel” with surrounding jaw bone, which undergoes necessary and unavoidable changes throughout a person’s life. But a new technique pioneered in the Tissue Engineering and Regenerative Medicine Laboratory of Dr. Jeremy Mao, Edward V. Zegarelli Professor of Dental Medicine, and a professor of biomedical engineering at Columbia University, can orchestrate the body’s stem cells to migrate to three-dimensional scaffold that is infused with growth factor. This can yield an anatomically correct tooth in as soon as nine weeks once implanted in the mouth. “These findings represent the first report of regeneration of anatomically shaped tooth-like structures in vivo, and by cell homing without cell delivery,” Dr. Mao and his colleagues said in the paper. “The potency of cell homing is substantiated not only by cell recruitment into scaffold microchannels, but also by regeneration of a putative periodontal ligaments newly formed alveolar bone.” Dental implants usually consist of a cone-shaped titanium screw with a roughened or smooth surface and are placed in the jaw bone. While implant surgery may be performed as an outpatient procedure, healing times vary widely and successful implantation is a result of multiple visits to certified clinicians, including general dentists, oral surgeons, prosthodontists and periodontists. Implant patients must allow two to six months for healing and if the implant is installed too soon, it is possible that the implant may move which results in failure. The subsequent time to heal, graft and eventually place a new implant may take up to 18 months. The work of Dr. Mao and his laboratory, however, holds manifold promise: a more natural process, faster recovery times, and a harnessing of the body’s potential to regrow tissue that will not give out and could ultimately last the patient’s lifetime. By homing stem cells to a scaffold made of natural materials and integrated in surrounding tissue, there is no need to use harvested stem cell lines, or create a an environment outside of the body (e.g., a Petri dish) where the tooth is grown and then implanted once it has matured. The tooth instead can be grown “orthotopically,” or in the socket where the tooth will integrate with surrounding tissue in ways that are impossible with hard metals or other materials. “A key consideration in tooth regeneration is finding a cost-effective approach that can translate into therapies for patients who cannot afford or who aren’t good candidates for dental implants,” Dr. Mao said. “Cell-homing-based tooth regeneration may provide a tangible pathway toward clinical translation.” This study is published in the Journal of Dental Research, a top journal in the field of dentistry. This research was supported by NIH ARRA Funding via 5RC2 DE020767 from the National Institute of Dental and Craniofacial Research. For more information, visit dental.columbia.edu/. To read more about dental implants, go to www.dentistryiq.com/index/display/article-display/8259726870/articles/dentisryiq/industry/2010/05/biolux-osseopulse.html. To comment on this topic, go to community.pennwelldentalgroup.com/. Source: DentistryIQ
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03/10/2010 - From Dentistry IQ: Plasticity in stem cells -- a valuable property for the future of medicine
You can’t open a newspaper or watch TV without hearing about the incredible advancements in stem cell research, therapies, and applications. Today, this is made possible because of one of stem cells’ most valuable traits, their “plasticity,” — their ability to turn into specific tissues in addition to those from which they are derived. It’s this unique property that is helping transform medicine and dentistry, and shaping the future of regenerative medicine.

Aging is a degenerative process, and as we get older we lose the ability to naturally repair injured or damaged tissues. Stem cells are master cells found throughout our bodies and are responsible for repairing these tissues. Today, dentists in many countries are recovering these valuable stem cells from teeth.

Around the world, researchers are recognizing the plasticity of stem cells and devising ways to control and direct them into many different types of cells and tissues. These cells are then being used to repair damaged and injured tissues and organs. This is the emerging field of regenerative medicine, and it will revolutionize the practice of medicine and dentistry. Utilizing the body’s own repair and maintenance mechanisms, regenerative medicine holds the realistic promise of creating a new paradigm — away from the current “mitigation” approach to treating disease and trauma — to one focused on curing disease and rebuilding damaged tissues and organs.

There are many opportunities to recover stem cells from teeth, but the earlier they are recovered, the more potential they will have for future regenerative therapies. The stem cells recovered from teeth have proved to be very plastic, and they are being introduced into clinical trials.

In Italy researchers recovered stem cells from erupted third molars, expanded these cells in the laboratory, and then reintroduced these stem cells into the same individual from whom they were recovered to repair bone defects in the mandible. In Australia researchers are currently utilizing dental stem cells as a means to treat brain injuries and Alzheimer’s disease. They are observing positive therapeutic results in mice and hope to begin clinical trials using dental stem cells in humans within the next five years. In Japan researchers have differentiated dental stem cells into hepatocytes that might one day be used to treat liver disease. Out of Brazil come published reports that researchers have used dental stem cells to treat dogs with muscular dystrophy. And in Spain researchers are using dental stem cells to treat cardiac disease in animals.

One day, these successful therapies will be applied to humans.

Regenerative medicine

Regenerative medicine is based on three things: stem cells or the raw materials; the extrinsic or intrinsic factors, which tell the stem cells what type of tissue to become; and natural or manufactured scaffolds, which define the shape of growing tissue.

There are several approaches to regenerative medicine. One is in vivo, to introduce extrinsic factors and scaffolds that will home the body’s own natural stem cells to the site of injury. In the body, or in vivo, plasticity is not thought to occur on its own. The stem cells are recruited locally and generally from the type of tissue that they are found in. In degenerative diseases, the local stem cells do not have the capacity to produce enough progenitor cells to repair the damaged tissue.

One of many future solutions is to introduce tissue-specific stem cells to repair these compromised tissues and organs. This will require an accessible source of stem cells that can be programmed into the specific tissue type needed to be repaired. The best cells to use would be an individual’s own stem cells, cells that would be recognized as self and would not be rejected or require the individual to take immunosuppressive medications.

Accessibility

Dental stem cells are proving to be an accessible source of stem cells that have the plasticity to turn into varied types of tissues. Researchers have differentiated dental stem cells in their laboratories into progenitor cells that can produce bone, cartilage, adipose, nervous tissue, muscle, hair, and insulin just to name a few. They have designed tissue-specific “cocktails” which are introduced into the culture medium, directing the stem cells into the desired tissue type.

The dental stem cells are recovered from recently extracted healthy teeth, notably deciduous teeth, developing third molars, and other permanent teeth. Every child will have 20 primary teeth replaced by permanent teeth. In the United States alone, more than 10 million wisdom teeth are being removed and discarded as medical waste on a yearly basis. There are numerous research articles published from around the world that characterize the stem cells recovered from the different types of teeth.

Stem cells recovered from deciduous teeth are immature stem cells that have different characteristics from stem cells recovered from permanent teeth. Deciduous teeth are ectomesenchymal in origin that begin formation at six weeks in utero. They have been shown to contain markers for factors that are found in embryonic stem cells. These factors are responsible for maintaining the “stemness” of these cells, or the ability to replicate indefinitely in vitro or outside of the body.

Unique properties

The proprieties of stem cells recovered from the pulp of deciduous teeth are different from those found in permanent teeth and have been labeled SHED cells for Stem cells from Human Exfoliated Deciduous teeth. SHED cells have also been shown to be more proliferative than bone marrow stem cells. When grown in culture, the SHED cells expand faster and for a longer period of time, generating a larger quantity of cells when compared to bone marrow stem cells.

Stem cells from developing third molars and other developing permanent teeth, e.g. bicuspids removed for orthodontic indications, are also very proliferative. The stage of development of these teeth will determine the potential for these stem cells. A wisdom tooth starts its development around the age of 4 years and begins calcification at the age of 7. The wisdom tooth is considered an organ; it includes nerves, blood vessels, ligaments, bone, enamel, dentin, and cementum. The development of the wisdom tooth starts at the bud stage where it is a collection of undifferentiated mesenchymal stem cells.

Timing

There are different schools of thought on when best to remove wisdom teeth. Removing a wisdom tooth at an earlier stage of development through a germectomy or tooth bud abortion will provide access to a tremendous quantity of pluripotential stem cells that display embryonic stem cell markers. As the wisdom tooth develops and calcifies, there become distinct areas of stem cells that differentiate to produce specific types of tissue.

Once the roots of the third molar begin to develop, there are three main areas of stem cells: the dental pulp, the periodontal ligament, and the apical follicle. When the permanent tooth is fully formed and has erupted, the stem cells are generally confined to the dental pulp. However, in situations where a tooth remains unerupted or impacted, the stem cell-containing follicle may still exist and can be recovered at the time of tooth removal.

As an individual matures, the pulp chambers in teeth also decrease in size. The blood supply within the pulp is reduced as well as the quantity of accessible mesenchymal stem cells. The order of teeth which have dental stem cells with the most potential are deciduous teeth, unerupted deciduous supernumerary teeth (mesodens), developing wisdom teeth, permanent teeth with continued root development (bicuspids or other healthy developing teeth that need to be removed for orthodontic indications), and fully developed and impacted wisdom teeth along with the follicle in adolescents and young adults. Also included are the dental pulp stem cells from healthy permanent teeth in adults.

Regenerative therapies are here today, and the plasticity of stem cells will mold the future of medicine and dentistry. Dental professionals are at the forefront of this emerging field. We have the opportunity to raise awareness of the benefits of stem cell research and provide our patients with the necessary information to make an informed decision on the value of preserving stem cells from healthy teeth when undergoing a planned dental procedure.
Read the entire article at Pennwell's Dentistry IQ:
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01/16/2010 - Dental stem cell grows human bone
Latest research puts dentists at the forefront of life-saving stem cell therapy.

When clinical research moves from animal to successful human trials, there is a level of certainty that the treatment modality being studied has reached a level of maturity that puts it well on the road to being safe and beneficial for the end recipient—the human patient. There is also the assumption that the trial involves the medical, not the dental community.

“This breakthrough clinical study uses the patients’ own stem cells harvested from their own teeth to repair bone. It is the first of what we believe will be an expanding number of applications to treat a broad array of diseases, traumas, and injuries,” said Art Greco, CEO of StemSave, a cryogenic dental stem cell bank headquartered in New York City.

“What we are seeing now is a rapid advancement in the use of stem cells in therapeutic and clinical applications all over the world. Every major nation around the globe is spending billions of dollars in developing stem cell-based therapies,” said Greco. One of the reasons Greco believes there is such urgency in the research is the aging world population. Without new healthcare treatment modalities, these nations will go bankrupt trying to treat the elderly conventionally. New therapies are needed to prolong life and keep people healthy, not just mitigate their illnesses.

“But the best stem cells for use in stem cell therapy are your own,” said Gregory Chotkowski, StemSave’s President. “By doing so, the risks of non-biocompatibility and tissue rejection are negated.”

StemSave and other companies like it are putting dentistry in the forefront of helping to save and preserve life. Those at StemSave believe stem cell banking will become the standard of care in the next two to five years.

Read the entire article


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12/08/2009 - First ever clinical study shows dental stem cells regrow bone
Leading stem cell company StemSave Inc applauds Italian scientists for breakthrough research that will forever change oral surgery.

NEW YORK – In a statement today, StemSave(TM), Inc., the market leader in the field of stem cell recovery and cryo-preservation lauds research published in the November issue of the European Cells and Materials Journal citing the reconstruction of the human mandible bone with autologous dental pulp stem cells.  StemSave commends Italian researchers from the 2nd University of Naples for their groundbreaking work.

This marks the first time dental stem cell research has moved from the laboratory to human clinical trials.  The repair and regeneration of bone is particularly significant for the oral maxillofacial field because the repair of these bones, which aid in orofacial functions like speech, chewing, swallowing and facial expressions are extremely intricate and complex.  

According to Dr. David Matzilevich, M.D., Ph.D., Science Advisor to StemSave, “these clinical studies are so significant because autologous dental stem cells were expanded in vitro and for the purpose of oro-maxillofacial bone repair.  These cells also facilitated the graft, eliminating immunologic complications such as rejection or excessive inflammation. This is compelling because it creates an environment which proves to be more favorable and successful for new mandibular bone to grow.  This approach also appears superior to current methodologies utilizing cadaverous tissue or grafting tissue from another part of the body.   I am very excited that dental stem cells have emerged as critical players in tissue engineering and regenerative medicine now that they have been proven to differentiate into multiple lineages.”

“This breakthrough clinical study, which uses the patient’s own stem cells harvested from their teeth to repair bone, is the first of what we believe will be an expanding number of applications to treat a broad array of disease, trauma and injury.  And because dental stem cells are easy to recover as part of routine dental procedures, this represents the first of many upcoming uses in the field of personal and regenerative medicine and supports the wisdom of banking your own stem cells from your teeth.” said Art Greco, CEO of StemSave, Inc. 
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11/13/2009 - Dr. Gregory Chotkowski, President of StemSave, Presenting at the Greater New York Dental Meeting, Wed. Dec 2nd
The repair of damaged and diseased tissues and the creation of new organs is no longer the future it is happening today.  Stem cells and regenerative therapies are an emerging field and the basis for “personalized medicine”.  The recent discovery of the valuable source of stem cells found in the pulp of healthy teeth presents new vistas to both medicine and dentistry.  These new opportunities will be explored during this presentation.

Title of the Presentation, Stem cells: Sources, Therapies, and The Dental Professional

What you will learn:
• The essentials of stem cell science
• The Current status of a non-invasive methodology for the recovery and cryopreservation of valuable and powerful adult stem cells residing within the pulp of healthy teeth and other oral tissues
• Modern applications of stem cell use in medicine and dentistry
• The role that the orthodontist and pediatric dentist will play in this exciting and emerging field.

Greater New York Dental Meeting, Wednesday Dec 2nd 4pm - 5pm

Program Details
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10/27/2009 - StemSave featured in ADHA's ACCESS: Dental Stem Cells in Research and Practice

StemSave is featured in the cover story of this month's Access Magazine, the Official Publication of the American Dental Hygienists' Association. Jean Majeski's comprehensive overview of the Stem Cell landscape in the Dental industry, the Hygienist's role in the process, and also features Gregory Chotkowski, DMD, President and co-founder of StemSave. Download the complete article here:

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09/29/2009 - StemSave at the upcoming 2009 AAOMS American Association of Oral and Maxillofacial Surgeons Annual Meeting

StemSave will be exhibiting at The American Association of Oral and Maxillofacial Surgeons (AAOMS) 91st Annual Meeting October 12th – 17th, 2009  in Toronto, Canada. We invite you to stop by Booth #2235 and allow us the opportunity to introduce you to the StemSave™ dental stem cell recovery and cryopreservation service. Built for Dental Professionals, by Dental Professionals, The StemSave Advantage can enhance your practice and expand the level of care that you already offer to your practice’s highly-valued patients.

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08/12/2009 - StemSave is featured on WPVI ABC 6 News in Philadelphia.
If parents missed the chance to bank their children’s umbilical cord blood, they now have the opportunity to bank their children’s stem cells found in teeth. WPVI ABC News reports Carolina Coll, a mother in Philadelphia, PA missed the opportunity to bank her older child’s umbilical cord blood but was able to bank his teeth stem cells thanks to her dentist, Dr. Gomez utilizing StemSave’s stem cell banking service. Margaret Keller, Associate Professor at Coriell Institute and director of Coriell Stem Cell Biobank, states that these stem cells have the potential to be differentiated into bone, heart, muscle and other tissue for use in future regenerative medical therapies.

Click Here to view the video
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05/30/2009 - Google Director Christopher Theodoros Joins StemSave Senior Management Team

StemSave(TM), Inc, a market leader in the field of stem cell recovery and cryo-preservation, announces today that S Christopher Theodoros has joined its senior management team. Theodoros, recently Director of Industry Relations for Google, Inc., will be responsible for leading StemSave’s growth and leadership in the biotech field as well as spearheading innovative digital marketing efforts.

“Chris joins at a crucial time for StemSave as we’re seeing renewed interest and investment from the Obama administration and heightened interest and investment from the private sector in the field of stem cell research,” said Art Greco, CEO of StemSave. “Stem cell research, technology and medicine are advancing at an exponential pace and StemSave gives people the ability to tap into those innovations by providing an affordable and non-invasive method for the recovery and cryo-preservation of the powerful adult stem cells found in teeth by teaming up with dentists to recover stem cells during routine dental procedures.

Chris brings a level of expertise and insight from growing early stage companies that will help lead StemSave’s ramp up during these exciting times where StemSave makes it possible for anyone with access to a dentist to have the ability to procure their own stem cells for use in future regenerative medical therapies.”

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03/24/2009 - Stem Cells in Teeth Open New Possibilities for Dental Practices - Article featured in WDJ written by Gregory Chotkowski, DMD, OMS, President, StemSave Inc.

In research centers, universities, and hospitals around the world, there are remarkable scientific advancements giving families the ability to recover valuable stem cells for use in future regenerative medical applications With the recent discovery of powerful stem cells within deciduous teeth and third molars, both children and adults now have the opportunity to recover and cryo-preserve their stem cells both noninvasively and affordably, giving dentists the opportunity to be on the frontlines of medicine’s most exciting developing field.

Dentists can now play a larger role in their patient’s overall health by assisting them in the recovery and cryo-preservation of the patient’s own very powerful stem cells. Introducing StemSave into a dental practice gives dental practitioners an opportunity to delve deeper into their patients’ health concerns and to offer a valuable service that transcends oral health. Indeed, it speaks to the future health of the entire being.

Stem cells are unique in that they are the only cells in our body that can regenerate. They are the repair and maintenance cells of the body and are the key to unlocking the promise of regenerative medicine. The foundation of this type of medicine is based on the body’s own natural reparative abilities; the stem cells’ abilities to replace damaged tissue caused by aging, disease, and injury. Another unique feature of certain types of stem cells is their ability to differentiate, meaning that in addition to their ability to regenerate, they can turn into a broad range of specialized cells. This enables stem cells to regenerate organs, tissues, bones, and much more. We are witnessing stem cell therapies being developed to treat disease and trauma such as Parkinson’s, Alzheimer’s, diabetes, MS, arthritis, heart disease, spinal cord injuries, joint replacement, genetic diseases, and many more.

Read entire article in the WDJ

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03/18/2009 - StemSave Exhibiting at the 97th Thomas P. Hinman Dental Meeting March 19-21, 2009 - Atlanta, Georgia
It was great meeting you at the Hinman Dental Meeting in Atlanta.  For those of you that visited our booth, and would still like to recieve the complimentary Code  for the 4-Credit CE Course entitled: Stem Cells: Sources, Therapies and the Dental Professional, please contact us at info@StemSave.com or call us at 877.StemSave.com.   We look forward to seeing you again next year.
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03/04/2009 - New York State Dental Foundation launches online CE course on stem cells and the dental professional
The repair of damaged and diseased tissues and the creation of new organs is no longer the future, it is happening today.  Daily, we hear the media reporting on stem cell breakthroughs and how they are being applied clinically to save lives.  Stem cells and regenerative therapies are an emerging field and the basis for "personalized medicine".  Dental Professionals have the opportunity to participate at the genesis of this new and exciting area of biotechnology.  

Dr. Gregory Chotkowski, DMD will present on the recently discovered and valuable source of stem cells found in the pulp of healthy teeth.  His discussion will include basic stem cell science, the current research and the future they hold for both Dentistry and Medicine

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03/02/2009 - Stem Cells: What will they be when they grow out?

Scientists are now developing a number of strategies in the laboratory for producing dopamine-releasing neurons from human adult stem cells to be transplanted into humans with Parkinson's disease. If the generation of an unlimited supply of dopamine-producing neurons is successful, neurotransplantation may be widely available for Parkinson's patients in the future.

Parkinson's disease is just one of many previously incurable diseases and conditions that may find a cure in stem cell regenerative therapies. Muscular dystrophy, Alzheimer's disease, osteoporosis, diabetes, cardiovascular disease, renal failure, and spinal cord injuries are a few others. Virtually any disease that occurs as a result of damaged, failing or malfunctioning tissues may potentially be cured through regenerative therapies.

Stem cells from one part of the body will be expanded (grown out) and reimplanted to replace an entirely different type of tissue. This type of transplant will totally negate the need for antirejection drugs, since the implant is made of the patient's own body cells.

Jeremy Mao, DDS, PhD, a professor and director of the Tissue Engineering and Regenerative Medicine Laboratory and professor of dentistry at Columbia University, states that, although more clinical research and differentiation studies are needed involving dental stem cells, the future holds a great potential for the use of these cells. Clinical research of the potential for utilizing these cells in the treatment of diseases or conditions involving neural, bone, cartilage, or fat is just beginning.

Dr. Mao's latest announcement states in an abstract that he has turned dental stem cells into pancreatic beta islet cells that produce insulin. Considering the fact that the occurrence of diabetes in the United States is reaching epidemic proportions, this is most exciting!

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02/27/2009 - Your Child's Teeth Can Save their Life using StemSave service - as found in Working Mother Magazine By Lauri Harrison
Wait! Before you plan for the tooth fairy to come and take away your child’s tooth, consider preserving it for future use  Believe it or not, the human tooth contains healthy pulp tissue which contains stem cells that can be utilized to regenerate your child’s health if needed. Sounds like a Sci-Fi movie, but it’s not. It works along the same principles as preserving the cord blood when your baby is born. Stem cells extracted from the healthy tissue within your child’s tooth can help fix medical ailments, grow new organs, repair bone, and much more.

There are more than 70 people currently in clinical trials right now, and the potential is incredible. Science is moving forward very quickly. Stem cells from teeth are a back-up insurance plan for your child. You don’t have to sacrifice a tooth. In fact, you work with your dentist to ensure that a healthy, loose tooth is taken out while there is still active blood supply to the tooth. The dentist can put up to four teeth in a vial that contains nutrients to keep the stem cells alive, and puts the teeth into hypothermia. The vial is shipped overnight to a company called Stem Save for preservation until you need it. The teeth are saved for your child and are not used for research. This whole process is coordinated with your dentist and Stem Save. All you have to do is set up the account, which can be done completely online. Stem Save and your dentist take care of everything for you.

If at some point in the future your child would need an organ transplant, bone marrow, skin, etc., their body will not run the risk of rejecting those from a donor because their own stem cells would be utilized. Currently, the Army is utilizing this method to help wounded soldiers heal from their injuries.

What exactly are stem cells? They are the carriers for repaired DNA and are capable of replicating themselves. Research studies have discovered that stem cells from teeth are some of the most powerful stem cells in the entire human body.  Interestingly, these stem cells can replicate at a faster rate and for a longer period of time than stem cells which have been harvested from other tissues within the body. As your body ages, the regenerative capabilities slow down so the earlier in life the stem cells are obtained, the more valuable they will be when they are needed most.

What will storing your family's stem cells from teeth do for you?
Protect your child’s future health.
Practically eliminate the potential risk of cell rejection and other complications.
This is an opportunity that is available now, is safe, convenient and affordable.
Since younger stem cells grow faster and for longer periods of time, they have less potential for mutations. Therefore these stem cells will be more effective when needed for future regenerative therapies.   If you are curious and would like to learn more, visit StemSave.com and talk to your family’s dentist about this opportunity. Even if your dentist is not included in the web site directory, you can still have your dentist do this for you. New dentists are added each and every day.

Think about all the teeth that have been collected and saved for baby books or just thrown away that could have been used. Its secondary insurance worth having, wouldn’t you agree?

Read entire article            Visit the MomToBeDepotBlog
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02/27/2009 - StemSave exhibiting at the 144th Midwinter Dental meeting in Chigago February 27th - March 1st.
Stop by booth #1060 to learn more about the StemSave Recovery and Cryopreservation service,  we will be handing out our CE course booklet Stem Cells: Sources, Therapies and the Dental Professionals.   Drop by, say hello and will provide you with a code to receive 4 complimentary CE credits.
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02/20/2009 - Saving lives one tooth at a time using the StemSave service
Researchers from the National Institute of Health discovered the presence of stem cells in teeth. Dentists familiar with the research formed a company called StemSave in order to store the stem cells from extracted teeth for later use if the patient needs to treat a disease or injury with stem cells - the body’s only natural regenerative cells which can grow many different types of tissue.

Dr. Robert Carpenter who owns a practice in Saratoga Springs has joined StemSave to become one of the first dentists in the area to collect and store personal stem cells for future use.  There are two types of stem cells, Carpenter said. First are the ever-controversial embryonic stem cells which come from human embryos, and second are adult stem cells which are already in every adult’s body and can regenerate into many different types of cells.
“There is a high quantity and quality of stem cells in teeth which are very ‘plastic,’ meaning they are easily multiplied and are easy to stimulate new growth in so many types of tissue,” he said.  Stem cells can be harvested in routine procedures that dentists perform every day in the office. The best stem cells come from adult wisdom teeth or baby teeth before they become loose. Once the teeth are extracted the cells are preserved and are stored for whenever the patient may need them.  What is unique about using stem cells from teeth is that the cells come from the patient’s own body, not someone else’s, like using embryonic stem cells. There is no chance that the body will reject the cells or become diseased.  “The potential here is unbelievable. We really are at the tip of the iceberg in realizing what we can do with these stem cells,” Carpenter said. “And to think that they are readily available with procedures that are done every day.”

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02/11/2009 - Pulling Stem Cells from wisdom teeth - Oral Surgeon utilizes StemSave

Many Individuals are willing to pay the money to preserve their teeth and for the chance of a cure later in life. Dr. John Lupori of Alpine Oral and Facial Surgery in Steamboat Springs first collected teeth for a storage bank several weeks ago and has done it a few times since then.

For Miriam Pensack’s family, it wasn’t a difficult decision.

The 17-year-old from Steamboat Springs has the same heart condition that caused her father to get a heart transplant. She was unconscious at Lupori’s office, about to get her wisdom teeth pulled, when her dad learned about StemSave, a New York company that stores dental stem cells.

“If, God forbid, I needed a heart transplant, . . . we think stem cells would be hugely beneficial,” said Pensack, who learned through genetic testing that she had inherited hypertrophic cardiomyopathy, a disease of the heart muscle that can cause sudden death in athletes.

The teenager’s father, physician and psychiatrist Robert Pensack, said he wasn’t thinking just of Miriam’s heart condition when he decided to save her dental stem cells.

“It’s my personal belief that stem cells are going to revolutionize medicine,” he said. “As she ages, as all of us will, she could come down with all kinds of other illnesses.”

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02/03/2009 - Banking Stem Cells For Future Use - StemSave and Fast Company Magazine
A personal banking system for stem cells

We’ve all heard about the promise of stem cells: Chinese doctors are experimenting with treatments for neurological diseases, and Spanish surgeons made headlines last fall after they grew a new section of windpipe for a woman using her own cells. While much of the research and most of the therapies are still figments of scientists’ imaginations, a New York-based company called StemSave is offering to bank your own cells in anticipation of the day when potential is turned into reality.

StemSave harvests stem cells from teeth already pulled by your dentist, which are delivered to its lab in a patented transportation kit that keeps cells alive by chilling them. All stem cells aren’t created equal, but StemSave CEO Art Greco claims that cells from teeth are particularly versatile — and the younger the tooth, the better. The service costs $590 to join, and $100 per year after that.

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02/02/2009 - Doctor in Colorado utilizes StemSave to preserve stem cells in wisdom teeth to combat a rare genetic cardiac disorder.

Miriam Pensack went to Alpine Oral and Facial Surgery to have her wisdom teeth pulled in November, when she awoke she learned that her father had chosen to have her stem cells saved.

When Lupori removed Miriam’s teeth, he checked to make sure the pulp was there and put them into a preserving solution. The office shipped the teeth to New York. StemSave’s laboratory workers tested them for viable stem cells and stored Miriam’s tissue.

Pensack, a former emergency room doctor who now is a psychiatrist, didn’t hesitate when he learned he could have Miriam’s cells saved. He has hypertrophic cardiomyopathy, a condition in which the muscle of the heart is abnormal without an apparent cause. It’s genetic.

If stem cell research advances to the state he thinks it will, people could have diseased heart tissue

replaced with healthy tissue grown from their own cells.

One of the benefits of growing a new organ from your own stem cells is that you don’t have any risk of the body rejecting it, Pensack said. Pensack underwent a heart transplant because of his condition. He takes two drugs to keep his immune system from rejecting the organ. He takes 13 drugs to treat the side effects of those two.

“You take them forever, and they’re all like chemotherapy,” Pensack said. “They’re poisonous to other organs.”

Miriam said her family frequently discussed the potential of stem cells. She’s glad hers are on ice because they could help her deal with any medical issue she encounters.

“Hopefully, should complications come up in my health, that is a pretty firm pillar to lean on,” Miriam Pensack said.

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01/26/2009 - StemSave will be exhibiting at the Yankee Dental Conference in Boston January 29th - 31st.
It was great meeting you at the Yankee Dental Meeting in Boston.  For those of you that visited our booth, and would still like to receive the complimentary Code  for the 4-Credit CE Course entitled: Stem Cells: Sources, Therapies and the Dental Professional, please contact us at info@StemSave.com or call us at 877.StemSave.com.   We look forward to seeing you again next year in Boston.
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01/18/2009 - Stem Cells: How baby teeth can save your life
Dr Joanne Oppenheim is a Pediatric Dentist in Chicago and was featured in an article that appeared in Woman Dental Journal,  Stem Cells: How Baby Teeth Can Save Your Life.

The value of stem cells in the curing of so many of the deadliest diseases is much better understood today. If we can save the stem cells from baby teeth, it is like receiving another opportunity for the people who did not save their babies' cord blood.

In the spring of 2008, I read an article about preserving the stem cells from baby teeth. My first thought was that it was a waste having all of my children’s teeth sent to the tooth fairy instead of to StemSave. During the annual American Academy of Pediatric Dentistry meeting in May, I spoke with the people at the StemSave table. They were doing the same thing with baby teeth as the people 12 years ago were doing with the cord blood.

Once parents choose to save their child’s baby teeth, we explain to the child that we will give them a special tooth box and the tooth fairy will still come to their house. There is so much emotion and nostalgia associated with losing baby teeth. While parents may want to take the traditional under-the-pillow route with the first tooth, we try to create a new sense of excitement with sending the tooth off to StemSave. We encourage the child to draw a picture or write a note to let the tooth fairy know where the tooth is and that we only need the stuff on the inside and she can take the stuff on the outside!

Sources of Dental Stem Cells  In a child, the most accessible stem cells are from the oral cavity. For deciduous teeth, the best candidates are moderately resorbed canine and incisors with the presence of healthy pulp. In children, other sources of easily accessible stem cells are supernumerary teeth, mesodens, over-retained deciduous teeth associated with congenitally missing permanent teeth, and prophylactically removed deciduous molars for orthodontic indication.

Read the entire WDJ article


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01/08/2009 - Doctors recommend StemSave for banking stem cells from teeth for those parents who missed the opportunity to save their children’s cord blood
As seen on the nationally syndicated CBS program ‘The Doctors,’ powerful stem cells found in teeth provide parents with a ‘second opportunity’ to save stem cells.

View ‘The Doctor’s’ Video


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12/27/2008 - StemSave president Dr. Greg Chotkowski discusses stem cells, regenerative medicine and the recovery and cryo-preservation of stem cells found in teeth on AM Arizona.
StemSave, Inc is a collaborative effort between stem cell researchers and the dental community to provide families, individuals and stem cell researchers a cost effective, non-invasive methodology for the recovery and cryopreservation of powerful and valuable Adult Stem Cells residing within baby teeth, wisdom teeth, permanent teeth and other oral tissues for future use in personalized medicine and regenerative medical therapies. For more information, visit www.StemSave.com.

View the AM Arizona Video
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12/09/2008 - Fox News Report Stem Cells in teeth could potentially save lives.
A Phoenix Oral Surgeon and a StemSave Dental Professional, Dr. Jack Buhrow,  provides the StemSave Recovery and Cryopreservation Service for a 21 year old woman at the time her wisdom teeth are being extracted. The Stem Cells contained in the healthy pulp of teeth could be used for future regenerative purposes.

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12/08/2008 - StemSave and Hu-Friedy announce partnership on stem cell education
NEW YORK, NY, October 21, 2008 – StemSave(TM), Inc, a market leader in the
field of stem cell recovery and cryo-preservation, announced today its partnership
with Hu-Friedy’s online dental hygiene community, Friends of Hu-Friedy to offer a new continuing education (CE) course on the role dental professionals can play in both the recovery and future use of stem cells.

The CE class was developed in collaboration with StemSave’s president, Dr. Gregory Chotkowski, DMD, OMS and is titled: Stem Cells: Emerging Medical and Dental Therapies and the Dental Professional. StemSave and Hu-Friedy are making the  course complimentary to registered members, known as ‘friends of Hu-Friedy’, until the end of October.
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11/22/2008 - DISCOVERY OF STEM CELLS IN TEETH PUTS DENTISTRY AT THE FOREFRONT OF THE EMERGING FIELDS OF REGENERATIVE AND PERSONALIZED MEDICINE

Columbia University professor Dr Jeremy Mao to present his research findings on dental stem cells & Discuss the medical, health care and business implications of preserving patients’ dental stem cells

Presented at the Greater New York Dental Meeting (GNYDM), Jacob K Javits Center in New York City,  Wednesday, December 3rd at11:45am.

More than 55,000 health care professionals will gather at the Greater NY Dental Meeting where Dr. Jeremy Mao, DDS, PhD will discuss the medical applications of dental stem cells and how dentists can incorporate this groundbreaking discovery into their practices. 

Dentists are now in the unique position of being able to help patients preserve their own stem cells.  Instead of discarding a patient’s tooth during a routine medical procedure, a new technology allows dentists to preserve these teeth so patients can bank their stem cells.

Dr. Mao, one of the leading stem cell researchers in the world, will discuss his latest scientific findings and why dentists should expand their practice to incorporate the recovery and cryo-preservation of dental stem cells on behalf of their patients.

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10/21/2008 - THE FRIENDS OF HU-FRIEDY PROGRAM LAUNCHES A NEW CONTINUING EDUCATION COURSE: Stem Cells: Emerging Medical and Dental Therapies and the Dental Professional

CHICAGO, IL – Hu-Friedy’s online dental hygiene community, Friends of Hu-Friedy  is designed exclusively for RDHs, dental hygiene students and faculty, the program, which offers professional support for its members in various ways, now includes complimentary CE courses. The membership program’s CE catalog currently offers multiple courses with the newest addition titled: Stem Cells: Emerging Medical and Dental Therapies and the Dental Professional. As a special introductory offer, Stem Cells: Emerging Medical and Dental Therapies and the Dental Professional will be complimentary to all members (no Hu-Points needed to redeem for credit!) now through October 31st , 2008!

The 2 CEU course was developed in collaboration with Dr. Gregory Chotkowski, DMD, president of StemSave, Inc. The course centers on how the dental professional will play an important role in both the recovery and the future use of stem cells in Dental and Medical regenerative and personalized therapies.  

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10/20/2008 - October 16th - 19th The American Dental Association's Annual Session, San Antonio TX

It was great meeting you at the ADA meeting in San Antonio.  For those of you that visited our booth, and would still like to recieve the complimentary Code  for the 4-Credit CE Course entitled: Stem Cells: Sources, Therapies and the Dental Professional, please contact us at info@StemSave.com or call us at 877.StemSave.com.   We look forward to seeing you again next year.

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10/19/2008 - Dentaltown - On Line CE - Stem Cells: Emerging Medical and Dental Therapies for the Dental Professional
Speaker:  Jay B Reznick, DMD, MD 

Synopsis: 

Recent exciting discoveries place dentists at the forefront of engaging their patients in potentially life-saving therapies derived from a patient's own stem cells located in deciduous and permanent teeth. Adult stem cells, including dental stem cells, have the potential, like bone marrow-derived stem cells and adipose-derived stem cells, to cure a number of diseases.

In medicine, stem cell-based treatments are being used and investigated for conditions as diverse as Parkinson's disease neural degeneration following brain injury, cardiovascular disease and autoimmune diseases. Stem cells will be used in dentistry for the regeneration of dentin and/or dental pulp, biologically viable scaffolds will be used for the replacement of orofacial bone and cartilage, and defective salivary glands will he partially or completely regenerated. Dental stem cells can he obtained from the pulp of the primary and permanent teeth, from the periodontal ligament, and from associated healthy tissues. Exfoliating/extracted deciduous teeth and permanent teeth extracted for orthodontic treatment, trauma or dental implant indications are all readily available sources of dental stem cells. The harvest of these dental stem cells results in minimal trauma. Dental professionals have the opportunity to make their patients aware of these new sources of stem cells that can be stored for future use as new therapies are developed for a range of diseases and injuries.
Dentaltown - On Line CE - Stem Cells:
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09/20/2008 - StemSave, Inc. Moves Corporate Headquarters to New York City
NEW YORK, NY, Sep 16 (MARKET WIRE) --
StemSave(TM), Inc, a market leader in the field of stem cell recovery and cryo-preservation, announced today that effective immediately, it is moving its corporate headquarters to New York City (its lab and cryo-preservation facilities will remain in Massachusetts). Arthur E. Greco, CEO, made the announcement today from the company's new offices in Manhattan. "Not only does this move bring our corporate offices closer to our scientific advisors, it places us in one of the global epicenters of stem cell research. In addition, it allows us to participate in New York State's $600 million stem cell research initiative. This is an enormous opportunity for us and for the families we serve." StemSave's scientific advisory council includes Dr. Jeremy Mao, DDS, PhD, a Director of the Tissue Engineering and Regenerative Medicine Laboratory (TERML) and a Professor at Columbia University, and Gordana Vunjak-Novakovic, PhD, a Director of the Laboratory for Stem Cells and Tissue Engineering and Professor of Biomedical Engineering at Columbia University.

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09/18/2008 - September 16th - 20th The AAOMS 90th Annual Meeting, Seattle Washington

StemSave will be exhibiting at The American Association of Oral and Maxillofacial Surgeons 90th Annual Meeting September 16th – 20th, in Seattle, Washington.
 
We invite you to stop by Booth #1608 and allow us the opportunity to introduce you to the StemSave™ dental stem cell recovery and cryopreservation service. StemSave™ can enhance your practice and expand the level of care that you already offer to your practice’s highly-valued patients.



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09/17/2008 - Adelaide research to repair brain damage with stem cells from teeth

September 15, 2008 11:30pm

STROKE victims could one day give their back teeth to repair brain injuries, an Adelaide researcher predicts.

A team of scientists is investigating using stem cells harvested from adult teeth to repair brain damage.

It will be led by the newly created Centre for Stem Cell Research, which was launched yesterday at the University of Adelaide.

Almost 100 scientists and 80 students from 18 research groups across Adelaide are involved with the centre, which plans to develop therapies for diseases such as stroke, heart attack, cancer and cystic fibrosis.

It has been established that cells from adult teeth can be used to create stem cells that have the ability to form new brain tissue.

An experiment has begun to see whether these cells can repair stroke damage in the brains of rats.

Dr Simon Koblar of the University of Adelaide said human clinical trials would follow within five years if the experiments worked.

Dr Koblar said most of his patients in the clinic at Queen Elizabeth Hospital "would give gladly some of their teeth" to see even a small improvement in movement and brain function after a stroke.

"At the moment all I can do is, from day to day, say `wait and see'," he said.

Centre director Associate Professor Stan Gronthos was one of the first to realise that teeth stem cells were "a little bit different".

"They have the ability to form different structures in the craniofacial region including brain tissue as well," he said.

Researcher Dr Agnes Arthur helped prove stem cells from adult teeth could make brain cells. Her work has been published in the journal Stem Cells.

She said she wanted to do something that could have clinical implications, "down the track" and was happy with the way the research turned out.

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09/02/2008 - September 6-9 The American Academy of Periodontology's 94th Annual Meeting in Seattle Washington.

It was great meeting you at the AAP's 94th Annual Meeting September 6-9 at the Washington State Convention and Trade Center in Seattle.  For those of you that visited our booth, we will be emailing you the complimentary Code  for the 4-Credit CE Course entitled: Stem Cells: Sources, Therapies and the Dental Professional. We look forward to you enrolling as a StemSave Dental Professional.

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08/06/2008 - WEBCAST Stem Cells: Sources, Therapies and the Dental Professional, Speaker: Fiona Collins, MBA, MA On-demand 30 minutes in length

Overview:

Recent exciting discoveries place dentists at the forefront of engaging their patients in potentially life-saving therapies derived from a patient's own stem cells located in deciduous and permanent teeth. In medicine, stem cell-based treatments are being used and investigated for conditions as diverse as Parkinson's disease, neural degeneration following brain injury, cardiovascular disease and autoimmune diseases. Stem cells will be used in dentistry for the regeneration of dentin and/or dental pulp, biologically viable scaffolds will be used for the replacement of orofacial bone and cartilage, and defective salivary glands will be partially or completely regenerated.

Dental stem cells can be obtained from the pulp of the primary and permanent teeth, from the periodontal ligament, and from associated healthy tissues. Exfoliating/extracted deciduous teeth and permanent teeth extracted for orthodontic treatment, trauma or dental implant indications are all readily available sources of dental stem cells. The harvest of these dental stem cells results in minimal trauma. Dental professionals have the opportunity to make their patients aware of these new sources of stem cells that can be stored for future use as new therapies are developed for a range of diseases and injuries.
 
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07/05/2008 - July 16th - 20th AGD Annual Meeting in Orlando Florida
It was great meeting you at The Academy of General Dentistry Annual Meeting.  For those of you that visited our booth, we will be emailing you the complimentary Code  for the 4-Credit CE Course entitled: Stem Cells: Sources, Therapies and the Dental Professional.  We hope you enjoyed Dr. Vanstrom's presentation
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05/05/2008 - May 22nd - 25th: The American Association of Pediatric Dentist, Washington, DC
It was great meeting you at the AAPD meeting.  For those of you that visited our booth, we will be emailing you the complimentary Code  for the 4-Credit CE Course entitled: Stem Cells: Sources, Therapies and the Dental Professional.  We look forward to seeing you again next year in Hawaii
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04/28/2008 - May 1st – May 4th: The California Dental Association’s Spring Scientific Meeting, Anaheim, CA
It was great meeting you at the CDA Spring Scientific meeting.   We look forward to seeing you again at the fall CDA meeting.
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04/19/2008 - April 17th – 19th: DentalTown’s 6th Annual Townie Meeting, Las Vegas, NV
It was great meeting you at the Townie Meeting.  For those of you that visited our booth, and would still like to recieve the complimentary Code  for the 4-Credit CE Course entitled: Stem Cells: Sources, Therapies and the Dental Professional, please contact us at info@StemSave.com or call us at 877.StemSave.com.   We look forward to seeing you again next year.
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04/14/2008 - 4/14/2008 Published Article: Stem Cells and the Future of Dental Care. Jeremy J. Mao, DDS, Ph.D, New York State Dental Journal, March 2008.

Abstract:

What are stem cells? As dentists, why should we be concerned with stem cells? How would stem cells change dental practice? Is it possible to grow a tooth or TMJ with stem cells? This article summarizes the latest stem cell research and development for dental, oral and craniofacial applications.  Stem cell research and development will, over time, transform dental practice in a magnitude far greater than did amalgam or dental implants.  Metallic alloys, composites and even titanium implants are not permanent solutions. In contrast, stem cell technology will generate native tissue analogs that are compatible with the patient’s own.

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04/14/2008 - April 3rd - 5th 2008 Western Regional Dental Meeting Phoenix AZ
Thank you for stopping by our booth and allowing us to introduce you to StemSave.  We look forward to seeing you again next year.
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